The UC-II® Story
UC-II® undenatured type II collagen was born out of a father’s need to help his daughter live a better life.*

*On file
That was over two decades ago. Since then, UC-II® undenatured type II collagen has been put to the test time and again in well-controlled human studies.
The results tell the real story.
Think support for tired, overworked joints so you can stay active and feel good.
uc-ii pill hand

Move Through Your Day With Ease

Stay Active

Helps you keep moving better than glucosamine + chondroitin.**

Stay Flexible

Helps you get up to 10% more range of motion in your knees compared to those who took a placebo.

Feel Good

Helps support joint comfort so you can keep doing the things you love to do.
**Lugo, et al. Nutr J. 2016;15:14.
†Lugo, et al. J Int Soc Sports Nutr. 2013;10.
How UC-II® Undenatured Type II Collagen Works
1
UC-II® ingredient travels intact to immune cells near the gut (Peyer’s Patch).
2
UC-II® ingredient activates immune cells (regulatory T cells) to recognize type II collagen.
3
When regulatory T cells recognize type II collagen in joint cartilage, they release bioactive compounds like TGF-beta and IL-10 .
4
In this way, UC-II® ingredient signals your body to rebuild and repair joint cartilage.
UC-II® IN THE MEDIA
LONZA US
UC-II® is among the ingredients that create unique joint-health products that addresses specific components of the articular system.
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LONZA EUROPE
Joint-health solutions like UC-II® are increasingly of interest to a broader array of consumer groups — from millenials to baby boomers.
LONZA US
UC-II® is proposed to initiate an immune cascade response which uses the body's natural repair mechanisms in the joints.
LONZA US
Lonza's Vice President of Platform Innovations, R&D talks about UC-II® science and its benefits for healthy aging.

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